Volume 5, Issue 1 (6-2023)
Tabari Biomed Stu Res J 2023, 5(1): 3-10 |
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Soltani F, Rezazadeh Bazaz E, Mashhadi F, Saadati Rad M T, Humphries H, Ghaffari Z et al . Evaluation of Serum Levels of Vitamin D in Patients with Vitiligo: A Case-Control Study. Tabari Biomed Stu Res J 2023; 5 (1) :3-10
URL: http://tbsrj.mazums.ac.ir/article-1-3797-en.html
URL: http://tbsrj.mazums.ac.ir/article-1-3797-en.html
Farnaz Soltani1 
, Esmaeil Rezazadeh Bazaz2 , Faezeh Mashhadi3 , Mohammad Taha Saadati Rad4 , Hannah Humphries5 , Zahra Ghaffari6 , Mitra Ayyasi * 7
, Esmaeil Rezazadeh Bazaz2 , Faezeh Mashhadi3 , Mohammad Taha Saadati Rad4 , Hannah Humphries5 , Zahra Ghaffari6 , Mitra Ayyasi * 7
1- Student Research Committee, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
2- Student Research Committee, School of Nursing and Midwifery, Islamic Azad University, Qochan Branch, Qochan, Iran.
3- Student Research Committee, School of Nutrition Sciences and Diet Therapy, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Psychiatry and Behavioral Sciences Research Center, Addiction Research Institute, Mazandaran University of Medical Sciences, Sari, Iran.
5- School of Nursing and Midwifery, Monash University, Melbourne, Australia.
6- Student Research Committee, School of Health, Mazandaran University of Medical Sciences, Sari, Iran.
7- Department of Nursing, School of Nursing and Midwifery, Islamic Azad University, Sari Branch, Sari, Iran.
2- Student Research Committee, School of Nursing and Midwifery, Islamic Azad University, Qochan Branch, Qochan, Iran.
3- Student Research Committee, School of Nutrition Sciences and Diet Therapy, Mashhad University of Medical Sciences, Mashhad, Iran.
4- Psychiatry and Behavioral Sciences Research Center, Addiction Research Institute, Mazandaran University of Medical Sciences, Sari, Iran.
5- School of Nursing and Midwifery, Monash University, Melbourne, Australia.
6- Student Research Committee, School of Health, Mazandaran University of Medical Sciences, Sari, Iran.
7- Department of Nursing, School of Nursing and Midwifery, Islamic Azad University, Sari Branch, Sari, Iran.
Abstract:
Introduction: Vitiligo is an autoimmune disease that is caused by the destruction of melanocytes and is appeared as depigmented patches on skin and mucosa. There have been various reports of serum Vitamin D levels in patients with vitiligo. The present study aimed to Evaluation of serum Vitamin D levels in patients with vitiligo.
Material and Methods: A case-control study was performed on 138 samples among people referring to Sabzevar Vasei clinic in the period of 2018-2019. The research units meeting the inclusion criteria were selected using convenience sampling and then divided into two group case and control (69 patients and 69 healthy people). After obtaining informed consent and completing the checklist of demographic characteristics, blood samples were taken from both groups and serum levels of Vitamin D in both groups were evaluated and compared. Data were analyzed using SPSS 20 via the independent t-test, chi-square test, Mann-Whitney test, Spearman correlation at a significance level of less than 0.01.
Results: In total, 131 participants completed the study; the two groups did not differ significantly in terms of age nor gender. At the end of the study, the mean of serum levels of Vitamin D in was significantly lower in the patients with vitiligo than in the people without vitiligo (P <0.001).
Conclusion: The results showed that serum Vitamin D levels in patients with vitiligo are lower than in those who do not have vitiligo. Therefore, it is recommended to measure the serum level of Vitamin D in these patients and if it is low, a treatment regimen should begin for these patients.
Material and Methods: A case-control study was performed on 138 samples among people referring to Sabzevar Vasei clinic in the period of 2018-2019. The research units meeting the inclusion criteria were selected using convenience sampling and then divided into two group case and control (69 patients and 69 healthy people). After obtaining informed consent and completing the checklist of demographic characteristics, blood samples were taken from both groups and serum levels of Vitamin D in both groups were evaluated and compared. Data were analyzed using SPSS 20 via the independent t-test, chi-square test, Mann-Whitney test, Spearman correlation at a significance level of less than 0.01.
Results: In total, 131 participants completed the study; the two groups did not differ significantly in terms of age nor gender. At the end of the study, the mean of serum levels of Vitamin D in was significantly lower in the patients with vitiligo than in the people without vitiligo (P <0.001).
Conclusion: The results showed that serum Vitamin D levels in patients with vitiligo are lower than in those who do not have vitiligo. Therefore, it is recommended to measure the serum level of Vitamin D in these patients and if it is low, a treatment regimen should begin for these patients.
Type of Study: Research (Original) |
Subject:
Nutrition
Published: 2023/06/1 | ePublished: 2023/06/1
Published: 2023/06/1 | ePublished: 2023/06/1
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