Tabari Biomedical Student Research Journal
Tabari Biomedical Student Research Journal
Tabari Biomed Stu Res J
Medical Sciences
http://tbsrj.mazums.ac.ir
1
admin
2423-6624
2423-6632
en
jalali
1398
9
1
gregorian
2019
12
1
1
4
online
1
fulltext
other
Effect of Salicylic acid on Phenols and flavonoids content and DPPH scavenging activity in cell suspension culture of
Iranian sodab (Ruta graveolens)
Adolescent Medicine
Research (Original)
Ruta graveolens, locally called sodab or sadab, is a known medicinal plant in north of Iran. The plant is a source for the production of secondary metabolites such as Glycosides, lignins, alkaloids, Coumarins, flavonoids and phenolic acids. In this work, the effect of salicylic acid on phenols and flavonoids contents of R. graveolens were investigated in the cell suspension culture. A significant enhancement in total phenolic and flavonoids contents were observed in salicylic acid treated samples. The results revealed that salicylic acid (10 mg/ml) showed as maximum as 3.14 fold enhancement in total flavonoid content (40.35 mg/g) and salicylic acid (20 mg quercetin equivalent/g of extract powder) showed as maximum as 18.33 fold improvement in total phenolic content (438.75 mg gallic acid equivalent/g of extract powder). Also in this study, salicylic acid (10 mg/ml) showed as maximum as 3.55 fold increase in DPPH radical-scavenging activity compared to control. These results suggest that the positive effect of salicylic acid on phenols and flavonoids content and DPPH scavenging activity in cell suspension culture. This effect was dose dependent
Salicylic Acid, Phenolic Content, Flavonoids, DPPH, Cell Suspension Culture, Ruta Graveolens, Sodab
18
21
http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3474-3&slc_lang=other&sid=1
Yaser
Sharifi
100319475328460028994
100319475328460028994
No
Msc. Department of Agricultural Biotechnology. Sari Agricultural Sciences and Natural Resources University, Sari, Iran.
Valiollah
Ghasemi Omran
100319475328460028995
100319475328460028995
No
Assistant Professor, Genetics and Agricultural Biotechnology Institute of Tabarestan, Sari Agricultural Sciences And Natural Resources University,Sari, Iran
Toktam Sadat
Tavabe Ghavami
100319475328460028996
100319475328460028996
No
Department of Genetics, Islamic Azad University, Science & Research Branch, Iran
Gorban Ali
Nematzadeh Gharakhili
100319475328460028997
100319475328460028997
No
Professor, Sari Agricultural Sciences And Natural Resources University, Sari, Iran.
Mohammad Ali
Ebrahimzadeh
zadeh20@gmail.com
100319475328460028998
100319475328460028998
Yes
Professor, Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute, Mazandaran University of Medical Sciences, Sari, Iran