en Public health Research (Original) <div style="text-align: justify;">Since the egression of the coronavirus 2019 (COVID-19) disease, more than 200 countries and areas around the world were affected. To the present, it is not clear whether COVID-19 has effects on thyroid function or not. The aim of the current study was to assess thyroid function in COVID-19 patients with history of thyroid disease and those without such a history and to find out the thyroid disturbance in both groups. The present study involved 86 COVID-19 affected patients admitted BioLab and the Balsam Hospital, Erbil/ Iraq between January and April 2021. Confirmation of COVID-19 infection all patients by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) of nasopharyngeal swabs. Thyroid hormones, and thyrotropin (TSH) level was analyzed and assessed. Most of the participants (88.4%) had normal T3 level, and there was no significant difference (p = 0.069) between those with normal T3, TPO and with no history of thyroid disease and those with such a history and/or high TPO. T4 levels of the participants with no history of thyroid disease and normal TPO did not differ significantly (p =0.725) from those with a history of thyroid disease and/or high TPO. Regarding the level of TSH, there was significant difference (p<0.001) between the two fore mentioned groups. There is high prevalence of subclinical hypothyroidism in the COVID-19 patients with family history of thyroid disease and high TPO antibody level.</div> COVID-19, RT-PCR, Subclinical hypothyroidism, Thyroid hormone, TSH 8 13 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3526-1&slc_lang=en&sid=1 Ali Hasan Mohammed ali.mohamed@hmu.edu.krd 100319475328460029931 100319475328460029931 Yes College of Dentistry, Hawler Medical University, Erbil, Kurdistan Region, Iraq. Araz Muhammed Yousif 100319475328460029932 100319475328460029932 No College of Dentistry, Hawler Medical University, Erbil, Kurdistan Region, Iraq. Samir Anwar Jabbar 100319475328460029933 100319475328460029933 No Erbil Teaching Hospital, Erbil, Kurdistan Region, Iraq. Parween Abdulsamad Ismail 100319475328460029934 100319475328460029934 No Education College, Salahaddin University, Erbil, Kurdistan Region, Iraq.