Tabari Biomedical Student Research Journal

en Prevalence of Adverse Transfusion Reactions in Hospitalized Patients in Tertiary Heart Center of Sari, Iran in 2014-2020 Allergy and Immunology Research (Original) Introduction: Our study aimed to determine the prevalence of adverse transfusion reactions (ATRs), unexpected or undesirable effects resulting from the therapeutic use of blood products. Material and Methods: In this cross-sectional study, we assessed the medical records of ATR patients who were referred to Mazandaran Heart Center from March 2014 until July 2020. Patients needed blood transfusions during the operation for various reasons; complications related to blood administration were considered ATR. Age, sex, associated clinical signs, symptoms, and adverse response were composed of a patient's file checklist with ethical points. SPSS 16.0 was used for statistical analysis. Results: In this study, 23,206 blood products were used in hospitals as treatment, and there were 96 reactions (4%) because of transfusion, and 10 patients had a history of recent reactions. There was not any specific connection between the age of patients and the existence of complications. Most reactions were allergic (44%) and non-hemolytic febrile reactions (42%). It is essential to state that 91% of adverse reactions were slight ones, and only 5% led to the injury. Out of 96 patients with complications, 79 patients received blood products as pack cells; 6 patients received Fresh Frozen Plasma; 3 patients received autologous blood products, while this number was one for Blood Low Leukocytes and platelets (PLT). Conclusion: Based on this investigation, the risk of adverse transfusion reactions (ATRs) is 4%, and universally 85 million units of blood products are transfused every year. Consequently, investigation to reduce this number is required. <div></div> Adverse transfusion reaction, Autologous, Blood transfusion 17 22 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3546-1&slc_lang=en&sid=1 Mehdi Bahrami mehdibah541@gmail.com 100319475328460030519 100319475328460030519 Yes Student Research Committee, School of Dentistry, Mazandaran University of Medical Sciences, Sari, Iran. Farzane Felehkari 100319475328460030520 100319475328460030520 No Student Research Committee, Department of Laboratory Sciences, School of Allied Medical Science, Mazandaran University of Medical Sciences, Sari, Iran. Mahdie Darvish-Khezri 100319475328460030521 100319475328460030521 No Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Ali Kheirandish 100319475328460030522 100319475328460030522 No Student Research Committee, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Aghil Mollaie 100319475328460030523 100319475328460030523 No Student Research Committee, School of Health, Mazandaran University of Medical Sciences, Sari, Iran. Mohammad Ahmadi 100319475328460030524 100319475328460030524 No Student Research Committee, Department of Laboratory Sciences, School of Allied Medical Science, Mazandaran University of Medical Sciences, Sari, Iran. Zahra Faghihian 100319475328460030525 100319475328460030525 No Department of Biochemistry, School of Medicine, Gorgan University of Medical Sciences, Gorgan, Iran. Hanie Mostafavi 100319475328460030526 100319475328460030526 No Student Research Committee, Department of Laboratory Sciences, School of Allied Medical Science, Mazandaran University of Medical Sciences, Sari, Iran. Pardis Karimnezhad 100319475328460030527 100319475328460030527 No School of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. Nima Ahmadi Nik Jouneghani 100319475328460030528 100319475328460030528 No Student Research Committee, School of Allied Health Sciences, Mazandaran University of Medical Sciences, Sari, Iran. Soheil Azizi s.azizi@mazums.ac.ir 100319475328460030529 100319475328460030529 No Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Cardiovascular Research center, Mazandaran University of Medical Sciences, Sari, Iran.