en Pharmacognosy (Medication from Natural Sources) Review <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><i><span style="font-size:11.0pt">Ziziphora clinopodioides</span></i><span style="font-size:11.0pt">, also known with vernacular names such as Kakuti-e kuhi, Pinah kuhi, Ankh, Lip vanilla, and mountain mint, is a wild flowering plant that belongs to the Lamiaceae family. It is used in treating typhoid fever, stomach strengthening, abdominal pains, inflammatory and cardiovascular disease, asthma, cough, bronchitis, insomnia, colds, flu, and other infectious diseases in traditional medicine. Additionally, <i>Z. clinopodioides</i> has various biological activities, including antibacterial, antimicrobial, anti-inflammatory, antioxidant, appetizer, carminative, antiseptic, and wound-healing properties. In this study, the antifungal activities of <i>Z. clinopodioides</i> were summarized. The Keywords were searched in Scopus until 19 October 2021 and the articles that contain relevant information about the antifungal activity of <i>Z. clinopodioides</i> were included. <i>Z. clinopodioides </i>leaf and aerial parts had significant antifungal activity against<i> Aspergillus flavus</i>,<i> Aspergillus parasiticus</i>, <i>Candida albicans</i>, <i>Candida glabrata</i>, <i>Candida</i> <i>guilliermondii</i>, <i>Candida</i> <i>krusei</i>,<i> Epidermophyton floccosum</i>,<i> Microsporum canis</i>, <i>Microsporum</i> <i>gypseum</i>,<i> Trichophyton mentagrophytes</i>,<i> Trichophyton rubrum</i>, and <i>Trichophyton schoenleini</i>.<i> </i>In some studies, its effects were higher than standards (such as amphotericin B, fluconazole, nystatin, and terbinafine). Therefore, it seems that <i>Z. clinopodioides</i> can be a good choice for more experimental and clinical studies as an antifungal agent.</span></span></span> Antifungal Agents, Candida albicans, Candida glabrata, Mountain Mint, Ziziphora clinopodioides 0 0 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3529-2&slc_lang=en&sid=1 Mohammad Eghbali mohammadeghbali1996@gmail.com 100319475328460030655 100319475328460030655 No Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Amirhosein Arab amirhoseinab34@gmail.com 100319475328460030656 100319475328460030656 No Student Research Committee, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Mohammad Hossein Hosseinzadeh iranmhhz@gmail.com 100319475328460030657 100319475328460030657 No Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Science, Sari, Iran. Fatemeh Bodaghabadi fatemehbodaghabady@gmail.com 100319475328460030658 100319475328460030658 No School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Mohammad Ali Ebrahimzadeh zadeh20@gmail.com 100319475328460030659 100319475328460030659 Yes Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Science, Sari, Iran.