en Infectious Diseases Case Report/Case Series <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="color:#002060">Introduction:</span></span></b> <span style="font-size:11.0pt">Herpes zoster, which is infected with varicella zoster virus (VZV), is a neurological infection and an immunodeficiency syndrome. Most patients who contact physicians complain of itchy and sometimes painful skin rashes. Herpes zoster, also known as &quot;shingles,&quot; results from the reactivation of VZV in the dorsal ganglia. Most skin patches occur on the hands or abdomen; rashes on the feet are rare. We aimed to report Herpes zoster presentation in the foot.</span></span></span><br> <span style="font-size:12pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="color:#002060">Case Presentation:</span></span></b> <span style="font-size:11.0pt">A 47-year-old male patient presented to private practice with a rash, itching, and pain in the left lower extremity for 3 days. He was diagnosed with herpes zoster and symptoms were relieved by the administration of acyclovir five times daily for one week. The patient was advised to use Calamine lotion, a cool bath, and a cold compress to relieve the pain and itching. On his next visit to the office, the rash on the left lower extremity disappeared after using the prescriptions and methods.</span></span></span><br> <b><span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:#002060">Conclusion:</span></span></span></b> <span style="font-size:11.0pt"><span new="" roman="" style="font-family:" times="">Considering that the prevalence of herpes zoster in the hands and feet is very low and only 7 cases have been reported in the world. This case was reported for the first time in Iran. Knowing the presentation of the disease and getting to know the patients&#39; complaints can help in timely diagnosis and control.</span></span> Foot, Herpes zoster, Limb, Shingles 42 45 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3569-1&slc_lang=en&sid=1 Hamed Jafarpour Hamed.jafarpour7@gmail.com 100319475328460031016 100319475328460031016 Yes Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Nazanin Reisi drnazaninreisi55@gmail.com 100319475328460031017 0009-0009-2357-3235 No Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Farzad Zeynali farzadzeynali2002@gmail.com 100319475328460031018 0009-0007-7751-0235 No Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Ali Anjam alianjam79@gmail.com 100319475328460031019 0009-0005-2394-1852 No Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Ahmad Tajallikhah ahmadtajallikhah@gmail.com 100319475328460031020 0009-0004-5789-9456 No Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.