en Gynecology and Infertility Review <span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Attention toward traditional medicine is increasing in recent years. Curcumin as an herbal polyphenolic compound has a therapeutic potential in supporting reproductive health and infertility. The effect of free radicals on male and female reproductive disorders is clear, and many of these problems lead to infertility. As a non-toxic substance, curcumin has antioxidant, anti-cancerو anti-inflammatory, etc. properties. Curcumin can neutralize free radicals and improve the quality of the target tissue. So it seems that the usage of curcumin and its analogs can be effective in treating many male and female reproductive diseases.</span></span></span> Curcumin, Antioxidant, ROS, Female reproductive system, Male reproductive system, Infertility 25 34 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3590-1&slc_lang=en&sid=1 Melika Izadpanah melikaizadpanah@yahoo.com 100319475328460031613 100319475328460031613 Yes Department of Anatomical Sciences, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran Zeinab Vahidinia z.vahidi1368@gmail.com 100319475328460031614 100319475328460031614 No 2Anatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran