en Virology Research (Original) <span style="font-size:11pt"><span style="line-height:200%"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Introduction: </span></span></span></b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Cytomegalovirus (CMV) is one of the most common infections among immunocompromised patients,</span></span></span> <span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">blood acceptors, and acceptors of organ transplantation. This study aimed to consider the prevalence of cytomegalovirus infection in hemodialysis patients.</span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:200%"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Material and Methods:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""> In this descriptive (cross-sectional) study, 80 blood samples were collected from hemodialysis patients who referred to Imam Khomeini hospital at Behshahr in 2017-2018. IgM and IgG titration against CMV was determined using a specific kit by ELISA method. </span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:200%"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Results: </span></span></span></b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">47 (58.75%) patients were male and 33 (41.25%) patients were female. The mean age of patients was 59.87 &plusmn; 14.38 year, while the mean of initial dialysis year for total patients was 92.12 &plusmn; 3.91. The mean of dialysis number for all patients was 1.15 &plusmn; 0.42 each week. During examination, all patients were positive anti-CMV IgG, while only 4 patients were positive anti-CMV IgM. There was no significant difference in antibodies titration between men and women. Approximately 4.25% of males and 6.06% of females were positive regarding to IgM and 100% of whom were positive for IgG. There was a relationship between the level of education and cigarette smoking with antibodies titrations; however it was not statistically significant.</span></span></span> <span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">There was no relationship between the antibody titer and dialysis duration. </span></span></span></span></span></span></span><br> <span style="font-size:11pt"><span style="line-height:200%"><span style="unicode-bidi:embed"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times="">Conclusion<i>:</i></span></span></span></b><span style="font-size:12.0pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""> Due to the relationship between hemodialysis and being positive anti-CMV IgG, CMV consideration in hemodialysis patients who receive blood products or undergo organ transplants (especially kidney transplant) is necessary. </span></span></span></span></span></span></span><br> &nbsp; Cytomegalovirus infection, Hemodialysis, IgM and IgG antibodies 1 10 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3620-1&slc_lang=en&sid=1 Mina Owrang mina.owrang@iau.ac.ir 100319475328460031926 100319475328460031926 Yes Departent of Medical Laboratory,Faculty of medical sciences,Sar,C.Islamic Azad University, Sari,Iran. Marzieh Yousefi trojeni yousefimarzieh89@gmail.com 100319475328460031927 100319475328460031927 No Behshahr Khatamolanbia Hospital, Mazandaran University of Medical Sciences, Sari, Iran