Tabari Biomedical Student Research Journal

en Molecular Diagnosis of class1 integron in Acinetobacter baumanii strains isolated from Patients admitted in hospitals of sari Microbiology Research (Original) Introduction: Acinetobacter baumannii, is an opportunistic and gram negative, anaerobic and non-fermentative bacteria. It's highly resistance to last line of antibiotics  and variable resistance pattern     in patients whose infected by this microorganism, makes a potential reason for recognition  related genes   and it help us to choosing the best strategy for using antibacterial substances in correct way. So, the aim of this study is molecular identification of integron class I in Acinetobacter baumannii strains in hospitalized patients in north of IRAN.   Material and Methods: 28 samples of   Acinetobacter baumannii were collected from hospitalized patients in burned and infected units of three hospitals in Sari during the 6 months from February to July of 2019. demographic information was collected from patients and susceptibility pattern of isolates was examined by Kirbey- Bauer method and presence of Integron class I were identified by PCR method. Results : In this study, the highest resistance and susceptibility to antimicrobial agents in strains with integrons, were related to Amikacin (95.2%) and Cefipim (90.5%), respectively. Frequency of  IntI  was 75% in all isolated strains. Most samples were related to wound but isolates from sputum were rare.   Conclusion: Upon on results of our study,the high resistance to different classes of antimicrobial    agents of isolates have been observed and so high prevalence rate of intI were existing. Statistical analysis showed correlation between integron class I and antimicrobial resistance in all isolates, too.   Acinetobacter baumannii, Antibiotic Resistance, Integron class I 11 19 http://tbsrj.mazums.ac.ir/browse.php?a_code=A-10-3620-2&slc_lang=en&sid=1 Mina Owrang mina.owrang@iau.ac.ir 100319475328460031928 100319475328460031928 Yes Departent of Medical Laboratory,Faculty of medical sciences,Sar,C.Islamic Azad University, Sari,Iran. Mirnaghi Fazeli Ghadi mirnaghifazeli@yahoo.com 100319475328460031929 100319475328460031929 No Departent of Medical Laboratory,Faculty of medical sciences,Sar,C.Islamic Azad University, Sari,Iran. Alamara Gholami alamara.Gholami@iau.ac.ir 100319475328460031930 100319475328460031930 No Department of Biological Sciences and Technologies,Faculty of Sciences, S