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URL: http://tbsrj.mazums.ac.ir/article-1-3478-en.html
2- Professor, Tehran University, Faculty of Veterinary Medicine, Department of Microbiology, Tehran, IR Iran
Background & Objectives: Pseudomonas aeruginosa is a leading cause of
Hospital-acquired infection worldwide. The organisms isolated are often resistant
to multiple antimicrobials particularly which are metallo-beta-lactamases (M&betaL)
producers. Therefore, the present study was designed to molecular detection of
Metallo-beta-lactamases genes in P. aeruginosa isolated from the burn patients.
Materials and methods: This descriptive, cross-sectional study was performed
between October to March 2014 on the 55 no duplicative and non-repetitive samples
collected from burn patients in Tehran, Iran. Multiplex-PCR assay was done in order
to detection of IMP ،VIM ،SPM ،GIM-1 and SIM-1 genes in the strains.
Results: The average age of the population studied was 49 years, with a range of
15 to 89 years. Forty-three (78.2%) were male and 12(21.8%) were female. the
distribution of the IMP ،VIM ،SPM ،GIM-1 and SIM-1 genes were 2(3.63%),
0(0.00%), 2(3.63%), 2(3.63%) and 0(0.00%), respectively.
Conclusion: M&betaL producing P. aeruginosa is an emerging threat in burn patients
and a cause of concern for physicians treating such infections.
Published: 2015/12/27 | ePublished: 2015/12/27
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