Volume 7, Issue 2 (12-2025)                   Tabari Biomed Stu Res J 2025, 7(2): 33-41 | Back to browse issues page

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Bouzari Z B, Lotfi Asrami F, Kavyani S, khonakdar A. Determining the predictive power of risk factors in the diagnosis of hyperplasia or endometrial cancer in women with abnormal uterine bleeding. Tabari Biomed Stu Res J 2025; 7 (2) :33-41
URL: http://tbsrj.mazums.ac.ir/article-1-3816-en.html
1- Department of Obstetrics and Gynecology, Infertility and Reproductive Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
2- Department of Biochemistry, Biophysics, Genetics and Nutrition, School of Medicine Metabolic Disorders Research Center, Golestan University of Medical Sciences.
3- Immunogenetic Research Center Non-communicable Diseases Institute
4-
Abstract:  
Background and purpose: The aim of the above study is to determine the predictive power of BMI in diagnosing hyperplasia or endometrial cancer in premenopausal women with bleeding.
Materials and methods: A case-control study in which all women ≤ 55 years of age (30) who were referred to Ayatollah Rouhani Hospital in Babol and underwent endometrial biopsy from 1400-1389 were included in the study. The information of the participants was recorded from the medical records of the patients. SPSS software version 18 was used to describe and analyze the data results. We considered a significance level of 0.05.
Results: In the above study, 314 women between the ages of 22 and 72 were included, with an average age of 45.59 ± 6.64 years. The average height of the patients was 160.72 ± 6.46 cm. Menstrual status was the only one that had a significant relationship with abnormal pathology (P=0.000). . There was no significant relationship between body mass index, average body mass index, ectopic pregnancy and infertility with abnormal pathology (P<0.05). None of the underlying diseases and breast cancer were related to abnormal pathology (P<0.05). Only age was a risk factor for abnormal endometrial pathologies and only age had a significant relationship with abnormal pathology (P=0.001).
Conclusion: suggests that age is a risk factor for developing EC. Therefore, for the elderly, especially those with EH aged ≥ 48 years, they should be treated with caution in clinical practice.
Type of Study: Research (Original) | Subject: Obstetrics and Gynecology
Published: 2025/12/19 | ePublished: 2025/12/19

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