Volume 5, Issue 4 (12-2023)
Tabari Biomed Stu Res J 2023, 5(4): 29-37 |
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Omraninava M, Mohammdi I, Owrang M, Hashempour H, Ashouri T, Rabiei Ghadi M M et al . Nasal Carriage Frequency and Antibiotic Resistance Pattern of Methicillin-Resistant Staphylococcus aureus Isolates from Operating Room Personnel of Valieasr Hospital, Qaemshahr, Iran. Tabari Biomed Stu Res J 2023; 5 (4) :29-37
URL: http://tbsrj.mazums.ac.ir/article-1-3829-en.html
URL: http://tbsrj.mazums.ac.ir/article-1-3829-en.html
Melody Omraninava *1 
, Iraj Mohammdi2 , Mina Owrang3 , Hashem Hashempour4 , Taha Ashouri5 , Mohammad Mahdi Rabiei Ghadi5 , Reza Najafi6
, Iraj Mohammdi2 , Mina Owrang3 , Hashem Hashempour4 , Taha Ashouri5 , Mohammad Mahdi Rabiei Ghadi5 , Reza Najafi6
1- Hospital Administration Research Center, Sari Branch, Islamic Azad University, Sari, Iran
2- Department of Basic Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
3- Microbiology Department, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
4- Anesthesiology Department, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
5- Department of Medical Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
6- Valieasr Hospital, Specific Clinic Medical Laboratory, Qaemshahr, Iran
2- Department of Basic Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
3- Microbiology Department, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
4- Anesthesiology Department, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
5- Department of Medical Sciences, Faculty of Medicine, Sari Branch, Islamic Azad University, Sari, Iran
6- Valieasr Hospital, Specific Clinic Medical Laboratory, Qaemshahr, Iran
Abstract:
Introduction: Staphylococcus aureus is recognized as a significant pathogenic agent in human diseases. Nasal carriage of Staphylococcus aureus is an independent risk factor for hospital-acquired infections, particularly surgical site infections. This study aimed to investigate the frequency and antibiotic resistance pattern of S. aureus strain isolates from the nasal carriage of operating room personnel in a referral hospital in Qaemshahr.
Material and Methods: This study was conducted on 65 personnel in the surgical and operating room departments (morning, evening, and night shifts) in 2022. The sampling method was census-based, and a checklist containing demographic information, underlying diseases, work history, history of antibiotic use, etc., was employed.
Results: The result of nasal swab culture in 10 individuals (15.4%) was positive. Also, the results showed a higher carrier frequency in the age group over 40 years (21.7%), among males (22.6%), in the nursing profession (15.56%), in personnel with more than 10 years of experience in the surgical department (24%), and with a work history in the hospital exceeding 13 years (25%). Furthermore, the results indicated higher sensitivity to rifampin and cefazolin in this descriptive study. Regarding clindamycin and oxacillin, relative sensitivity was observed.
Conclusion: In general, the results indicated that antibiotic resistance to ciprofloxacin, trimethoprim-sulfamethoxazole, erythromycin, clindamycin, and oxacillin was higher in Staphylococcus aureus infections. Therefore, it is suggested to investigate the causes of antibiotic resistance to these drugs to prevent further resistance compared to other antibiotics.
Material and Methods: This study was conducted on 65 personnel in the surgical and operating room departments (morning, evening, and night shifts) in 2022. The sampling method was census-based, and a checklist containing demographic information, underlying diseases, work history, history of antibiotic use, etc., was employed.
Results: The result of nasal swab culture in 10 individuals (15.4%) was positive. Also, the results showed a higher carrier frequency in the age group over 40 years (21.7%), among males (22.6%), in the nursing profession (15.56%), in personnel with more than 10 years of experience in the surgical department (24%), and with a work history in the hospital exceeding 13 years (25%). Furthermore, the results indicated higher sensitivity to rifampin and cefazolin in this descriptive study. Regarding clindamycin and oxacillin, relative sensitivity was observed.
Conclusion: In general, the results indicated that antibiotic resistance to ciprofloxacin, trimethoprim-sulfamethoxazole, erythromycin, clindamycin, and oxacillin was higher in Staphylococcus aureus infections. Therefore, it is suggested to investigate the causes of antibiotic resistance to these drugs to prevent further resistance compared to other antibiotics.
Type of Study: Research (Original) |
Subject:
Microbiology
Published: 2023/12/28 | ePublished: 2023/12/28
Published: 2023/12/28 | ePublished: 2023/12/28
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