Volume 6, Issue 4 (11-2024)
Tabari Biomed Stu Res J 2024, 6(4): 11-18 |
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Ethics code: IR.iau.sari.Rec.1402.078
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Kord R, Heydari I, Zafari M, Aghamohammadi A. Reproductive Risk Factors Associated with Breast Cancer: A Study of Iranian Women (2019-2020). Tabari Biomed Stu Res J 2024; 6 (4) :11-18
URL: http://tbsrj.mazums.ac.ir/article-1-3851-en.html
URL: http://tbsrj.mazums.ac.ir/article-1-3851-en.html
1- Department of medicine, Sari branch, Islamic azad university, Sari,Iran.
2- Department of Biology, Kerman branch, Islamic Azad University, Kerman, Iran
3- Assistant Professor, Health reproductive research center, Sari Branch, Islamic Azad University, Sari, Iran.
4- Assistant Professor, Department of medicine, sari branch, Islamic azad university, Sari,Iran.
2- Department of Biology, Kerman branch, Islamic Azad University, Kerman, Iran
3- Assistant Professor, Health reproductive research center, Sari Branch, Islamic Azad University, Sari, Iran.
4- Assistant Professor, Department of medicine, sari branch, Islamic azad university, Sari,Iran.
Abstract:
Introduction: Breast cancer constitutes a predominant contributor to cancer-related mortality among women on a global scale, with an observable escalation in incidence rates over recent decades. Principal risk determinants for breast cancer encompass advanced age, obesity, alcohol consumption, hormonal exposure, and genetic susceptibility. This investigation sought to elucidate the correlation between breast cancer and reproductive risk factors among women residing in Golestan Province, Iran, during the period spanning 2019 to 2020.
Material and Methods: A cross-sectional descriptive study was undertaken involving a cohort of 124 patients diagnosed with breast cancer. The research aimed to gather comprehensive data regarding several reproductive health milestones, specifically the age at which menarche occurred, the age at which participants experienced their first and last childbirth, as well as the age at which menopause was reached.
Results: The mean age of the participants in this study was 47.76 years. Notably, early onset of menarche and the utilization of oral contraceptives were identified as significant risk factors associated with breast cancer. Furthermore, the investigation revealed discernible patterns in both reproductive history and lifestyle factors among the cohort under examination.
Discussion and Conclusion: The findings presented highlight the significant role of reproductive factors in the etiology of breast cancer. It is imperative that further extensive, multicenter studies be conducted to clarify the intricate relationships between these reproductive factors and the associated risk of developing breast cancer. Specifically, early onset of menarche and the utilization of oral contraceptives merit additional scrutiny as potential focal points for preventive strategies.
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