Volume 6, Issue 4 (11-2024)                   Tabari Biomed Stu Res J 2024, 6(4): 1-10 | Back to browse issues page

Ethics code: IR.iau.sari.Rec.1402.089

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Brijani Karovai M, Yekani R, Homayoun M, Zafari M. Vitamin D Deficiency as a Risk Factor for Gestational Diabetes Mellitus. Tabari Biomed Stu Res J 2024; 6 (4) :1-10
URL: http://tbsrj.mazums.ac.ir/article-1-3852-en.html
1- Department of medicine, sari branch, islamic azad university, Sari,Iran.
2- Department of Biochemistry and Biophysics, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran,Iran. E-mail:Rezaayekani@gmail.com.
3- Department of biology, Faculty of sinces, Arsanjan branch, Islamic Azad university, Arsanjan, Iran.
4- Assistant Professor, Health reproductive research center, Sari Branch, Islamic Azad University, Sari, Iran.
Abstract:  
Introduction: Gestational diabetes mellitus (GDM) is a common complication affecting around 13.5% of pregnancies globally. This condition, characterized by insulin resistance and glucose metabolism disturbances, may be linked to vitamin D deficiency. A recent study aimed to investigate this potential connection to enhance prevention and treatment strategies.
Material and methods: From 2019 to 2020, a cohort study was conducted to assess the prevalence of vitamin D deficiency in pregnant women with GDM across different clinical settings. Participants were categorized based on their vitamin D status, excluding those with unclear levels or a history of diabetes. Precise diagnostic criteria were established, and data analysis was carried out using SPSS software.
Results: from the study of 100 pregnant women revealed a significant association between vitamin D deficiency and GDM. Those deficient in vitamin D, with an average age of 28.82 years and weight of 73.20 kg, showed higher rates of GDM compared to those with sufficient vitamin D levels (average age: 30.52 years, weight: 78.59 kg). This correlation was particularly notable among women aged 26 to 35 and those with normal or high body mass index (BMI). No significant associations were found with comorbidities, parity, or gravidity.
Discussion and Conclusion: Study shows 32% higher risk of GDM with low vitamin D levels vs normal levels (4%), especially in 26-35 age group. Larger, multi-center studies needed to confirm and build upon these findings due to limitations like sample size and regional scope.
Type of Study: Research (Original) | Subject: Nutrition
Published: 2024/11/20 | ePublished: 2024/11/20

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