Volume 7, Issue 1 (8-2025)
Tabari Biomed Stu Res J 2025, 7(1): 1-10 |
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Owrang M, Yousefi trojeni M. Prevalence of cytomegalovirus infection in hemodialysis patients in Imam Khomeini hospital at Behshahr. Tabari Biomed Stu Res J 2025; 7 (1) :1-10
URL: http://tbsrj.mazums.ac.ir/article-1-3881-en.html
URL: http://tbsrj.mazums.ac.ir/article-1-3881-en.html
1- Departent of Medical Laboratory,Faculty of medical sciences,Sar,C.Islamic Azad University, Sari,Iran.
2- Behshahr Khatamolanbia Hospital, Mazandaran University of Medical Sciences, Sari, Iran
2- Behshahr Khatamolanbia Hospital, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:
Introduction: Cytomegalovirus (CMV) is one of the most common infections among immunocompromised patients, blood acceptors, and acceptors of organ transplantation. This study aimed to consider the prevalence of cytomegalovirus infection in hemodialysis patients.
Material and Methods: In this descriptive (cross-sectional) study, 80 blood samples were collected from hemodialysis patients who referred to Imam Khomeini hospital at Behshahr in 2017-2018. IgM and IgG titration against CMV was determined using a specific kit by ELISA method.
Results: 47 (58.75%) patients were male and 33 (41.25%) patients were female. The mean age of patients was 59.87 ± 14.38 year, while the mean of initial dialysis year for total patients was 92.12 ± 3.91. The mean of dialysis number for all patients was 1.15 ± 0.42 each week. During examination, all patients were positive anti-CMV IgG, while only 4 patients were positive anti-CMV IgM. There was no significant difference in antibodies titration between men and women. Approximately 4.25% of males and 6.06% of females were positive regarding to IgM and 100% of whom were positive for IgG. There was a relationship between the level of education and cigarette smoking with antibodies titrations; however it was not statistically significant. There was no relationship between the antibody titer and dialysis duration.
Conclusion: Due to the relationship between hemodialysis and being positive anti-CMV IgG, CMV consideration in hemodialysis patients who receive blood products or undergo organ transplants (especially kidney transplant) is necessary.
Material and Methods: In this descriptive (cross-sectional) study, 80 blood samples were collected from hemodialysis patients who referred to Imam Khomeini hospital at Behshahr in 2017-2018. IgM and IgG titration against CMV was determined using a specific kit by ELISA method.
Results: 47 (58.75%) patients were male and 33 (41.25%) patients were female. The mean age of patients was 59.87 ± 14.38 year, while the mean of initial dialysis year for total patients was 92.12 ± 3.91. The mean of dialysis number for all patients was 1.15 ± 0.42 each week. During examination, all patients were positive anti-CMV IgG, while only 4 patients were positive anti-CMV IgM. There was no significant difference in antibodies titration between men and women. Approximately 4.25% of males and 6.06% of females were positive regarding to IgM and 100% of whom were positive for IgG. There was a relationship between the level of education and cigarette smoking with antibodies titrations; however it was not statistically significant. There was no relationship between the antibody titer and dialysis duration.
Conclusion: Due to the relationship between hemodialysis and being positive anti-CMV IgG, CMV consideration in hemodialysis patients who receive blood products or undergo organ transplants (especially kidney transplant) is necessary.
Type of Study: Research (Original) |
Subject:
Virology
Published: 2025/08/19 | ePublished: 2025/08/19
Published: 2025/08/19 | ePublished: 2025/08/19
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